Unit 2: Cell Membrane and Permeability - Practice Quiz

BTS118 — Cell Biology 60 Questions
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1 Which type of molecule forms the main structural layer of most cell membranes?

Chemical components of biological membranes Easy
A. Glycogen
B. Nucleic acids
C. Starch
D. Phospholipids

2 Which part of a phospholipid is attracted to water?

Chemical components of biological membranes Easy
A. The phosphate head
B. The amino acid chain
C. The fatty acid tail
D. The steroid ring

3 Which part of a phospholipid avoids water?

Chemical components of biological membranes Easy
A. The phosphate head
B. The sugar group
C. The glycerol head
D. The fatty acid tails

4 Which molecule helps regulate the fluidity of animal cell membranes?

Chemical components of biological membranes Easy
A. Cellulose
B. Cholesterol
C. DNA
D. Glycogen

5 What is the basic arrangement of phospholipids in a cell membrane?

Organization and Fluid Mosaic Model Easy
A. A carbohydrate bilayer
B. A protein monolayer
C. A phospholipid bilayer
D. A nucleic acid layer

6 Why is the cell membrane described as fluid?

Organization and Fluid Mosaic Model Easy
A. Its molecules can move sideways
B. It contains large water channels
C. It changes into a solid layer
D. Its molecules are permanently fixed

7 What does the term "mosaic" refer to in the fluid mosaic model?

Organization and Fluid Mosaic Model Easy
A. The presence of only one protein type
B. The shape of the nucleus
C. The arrangement of cell walls
D. The mix of different membrane molecules

8 Which membrane component is often found attached to the outside surface of proteins or lipids?

Organization and Fluid Mosaic Model Easy
A. RNA molecules
B. DNA strands
C. Cellulose fibers
D. Carbohydrate chains

9 What generally happens to membrane fluidity when temperature increases?

Fluidity of membranes and Factors that affect membrane Fluidity Easy
A. Fluidity disappears
B. Fluidity changes into rigidity
C. Fluidity becomes constant
D. Fluidity increases

10 Which type of fatty acid usually increases membrane fluidity?

Fluidity of membranes and Factors that affect membrane Fluidity Easy
A. Very long sugar chain
B. Unsaturated fatty acid
C. Saturated fatty acid
D. Phosphate-free fatty acid

11 What effect do saturated fatty acid tails usually have on membrane fluidity?

Fluidity of membranes and Factors that affect membrane Fluidity Easy
A. They decrease fluidity
B. They dissolve the bilayer
C. They remove proteins
D. They increase fluidity

12 What is the main effect of cold temperatures on a membrane?

Fluidity of membranes and Factors that affect membrane Fluidity Easy
A. The membrane becomes more fluid
B. The membrane becomes a carbohydrate layer
C. The membrane loses all lipids
D. The membrane becomes less fluid

13 Which membrane protein helps substances cross the membrane?

Membrane proteins and their functions Easy
A. Contractile protein
B. Transport protein
C. Storage protein
D. Digestive protein

14 What is one function of receptor proteins in a cell membrane?

Membrane proteins and their functions Easy
A. Storing genetic information
B. Making DNA copies
C. Digesting food particles
D. Receiving chemical signals

15 Which membrane protein can act as an enzyme?

Membrane proteins and their functions Easy
A. A cholesterol molecule
B. A phospholipid tail
C. A carbohydrate chain
D. An enzymatic protein

16 What is passive transport?

Active transport and passive transport Easy
A. Movement only through vesicles
B. Movement without cellular energy
C. Movement using ATP energy
D. Movement against all gradients

17 In which direction do substances usually move during diffusion?

Active transport and passive transport Easy
A. From the nucleus outward
B. From water to protein
C. From high to low concentration
D. From low to high concentration

18 What is required for active transport?

Active transport and passive transport Easy
A. Cellular energy
B. A concentration balance
C. Only oxygen gas
D. A cell wall

19 What is endocytosis?

Exocytosis and Endocytosis Easy
A. Breaking down membrane lipids
B. Taking materials into the cell
C. Moving water through a wall
D. Releasing materials from the cell

20 What is exocytosis?

Exocytosis and Endocytosis Easy
A. Moving particles through channels
B. Releasing materials from the cell
C. Taking materials into the cell
D. Making phospholipids in the bilayer

21 A membrane is exposed to a chemical that removes cholesterol while leaving phospholipids intact. Which change is most likely at moderate temperatures?

Chemical components of biological membranes Medium
A. The membrane gains more carbohydrate chains
B. The membrane becomes unable to form a bilayer
C. The membrane loses some control of fluidity
D. The membrane becomes less permeable to ions

22 Why do phospholipids spontaneously form bilayers in an aqueous environment?

Chemical components of biological membranes Medium
A. Their hydrocarbon tails attract surrounding water
B. Their phosphate groups avoid contact with water
C. Their proteins force the lipids into two layers
D. Their hydrophilic heads face water and hydrophobic tails avoid it

23 A membrane carbohydrate is attached directly to a lipid rather than to a protein. What structure has been formed?

Chemical components of biological membranes Medium
A. A lipoprotein channel
B. A glycoprotein
C. A phospholipid
D. A glycolipid

24 A researcher labels proteins on the outer surface of a cell and observes that many labels move laterally after several minutes. Which model best explains this observation?

Organization and Fluid Mosaic Model Medium
A. The fluid mosaic model
B. The fixed-layer model
C. The protein crystal model
D. The rigid wall model

25 A membrane protein is exposed to the cytoplasm on one side and the extracellular fluid on the other. Which property of the membrane does this demonstrate?

Organization and Fluid Mosaic Model Medium
A. Membrane asymmetry
B. Membrane crystallization
C. Uniform lipid distribution
D. Permanent protein immobility

26 A drug binds to membrane proteins but does not dissolve the phospholipid bilayer. Which membrane feature allows the drug to affect selected cell functions?

Organization and Fluid Mosaic Model Medium
A. The membrane has specialized proteins
B. The membrane is made only of carbohydrates
C. The membrane contains identical proteins
D. The membrane prevents all molecular movement

27 Two membranes contain the same number of phospholipids. Membrane X has more unsaturated fatty acid tails than membrane Y. At low temperature, which membrane should remain more fluid?

Fluidity of membranes and Factors that affect membrane Fluidity Medium
A. Membrane X, because its tails contain bends
B. Membrane Y, because its tails pack tightly
C. Membrane X, because its heads contain more phosphate
D. Membrane Y, because its tails contain fewer bonds

28 A cell adapted to a colder environment increases the proportion of unsaturated phospholipids in its membrane. What is the main benefit?

Fluidity of membranes and Factors that affect membrane Fluidity Medium
A. It maintains membrane flexibility
B. It increases the membrane's carbohydrate content
C. It blocks all small polar molecules
D. It reduces lateral lipid movement

29 If membrane temperature rises substantially, which change is most likely to occur without another stabilizing factor?

Fluidity of membranes and Factors that affect membrane Fluidity Medium
A. The phospholipids become proteins
B. The bilayer becomes more fluid
C. The hydrophobic tails become charged
D. The bilayer becomes completely solid

30 A cell accumulates a molecule inside using a membrane protein that changes shape after binding the molecule. Which function is being performed?

Membrane proteins and their functions Medium
A. Transport
B. Cell recognition
C. DNA replication
D. Membrane digestion

31 A membrane protein binds a signaling molecule outside the cell and triggers a response inside the cell without transporting the molecule across. What is its primary function?

Membrane proteins and their functions Medium
A. Receptor activity
B. Waste digestion
C. Structural storage
D. Phospholipid synthesis

32 A protein is attached to the inner surface of the plasma membrane but does not extend through the lipid bilayer. Which type of membrane protein is it?

Membrane proteins and their functions Medium
A. Peripheral protein
B. Lipid bilayer protein
C. Transmembrane channel
D. Integral protein

33 A molecule moves from an area of lower concentration to an area of higher concentration through a membrane protein. Which process is most likely involved?

Active transport and passive transport Medium
A. Simple diffusion
B. Facilitated diffusion
C. Active transport
D. Osmosis

34 A molecule crosses a membrane through a channel protein from high concentration to low concentration without ATP use. Which process describes this movement?

Active transport and passive transport Medium
A. Facilitated diffusion
B. Exocytosis
C. Primary active transport
D. Phagocytosis

35 A cell uses ATP to move sodium ions out of the cytoplasm even though sodium concentration is already higher outside. What does this process illustrate?

Active transport and passive transport Medium
A. Primary active transport
B. Solvent movement by osmosis
C. Movement through the lipid core
D. Movement down a gradient

36 A red blood cell is placed in a solution with a lower solute concentration than its cytoplasm. What is the most likely result?

Active transport and passive transport Medium
A. Solutes leave and the cell becomes rigid
B. Water enters and the cell swells
C. Water leaves and the cell shrinks
D. No water movement occurs

37 A membrane is permeable to water but not to a dissolved solute. Which condition would cause water to move into a cell?

Active transport and passive transport Medium
A. The solute can freely cross the membrane
B. The surrounding solution has no water
C. The cell has a higher solute concentration
D. The cell has a lower solute concentration

38 A secretory cell releases a protein outside the cell when a vesicle fuses with the plasma membrane. Which process is occurring?

Exocytosis and Endocytosis Medium
A. Exocytosis
B. Endocytosis
C. Simple diffusion
D. Osmosis

39 A cell surrounds and internalizes a large bacterium using extensions of its plasma membrane. Which type of endocytosis is this?

Exocytosis and Endocytosis Medium
A. Pinocytosis
B. Phagocytosis
C. Facilitated diffusion
D. Receptor-mediated exocytosis

40 A cell selectively takes in a hormone after it binds to a specific receptor concentrated in a coated membrane region. Which process is most likely involved?

Exocytosis and Endocytosis Medium
A. Primary active transport
B. Simple diffusion
C. Bulk-phase exocytosis
D. Receptor-mediated endocytosis

41 A membrane lipid has two fatty-acid tails: one saturated 18-carbon tail and one cis-unsaturated 18-carbon tail. Compared with a lipid containing two saturated 18-carbon tails, what is the most likely consequence at the same temperature?

Chemical components of biological membranes Hard
A. Higher transition temperature and greater fluidity
B. Lower transition temperature and reduced fluidity
C. No change because both lipids contain 18 carbons
D. Lower transition temperature and greater fluidity

42 A membrane is experimentally made more permeable to small nonpolar molecules without changing its protein content. Which alteration most directly explains this result?

Chemical components of biological membranes Hard
A. Increasing the fraction of unsaturated phospholipids
B. Increasing the fraction of phospholipids
C. Increasing the fraction of membrane carbohydrates
D. Increasing the fraction of peripheral proteins

43 Why does cholesterol reduce membrane permeability to small polar molecules while helping prevent phospholipid packing at low temperatures?

Chemical components of biological membranes Hard
A. Its fatty-acid tails create permanent pores through the bilayer
B. Its phosphate group forms covalent bonds with neighboring phospholipids
C. Its steroid rings fill gaps while its hydroxyl group remains near the surface
D. Its carbohydrate chains bind water and form an external diffusion barrier

44 A researcher treats intact red blood cells with a reagent that removes exposed carbohydrate groups but leaves proteins and lipids intact. Which function is most directly impaired?

Chemical components of biological membranes Hard
A. Movement of cholesterol between leaflets
B. Hydrolysis of ATP by cytosolic enzymes
C. Recognition during cell-cell interactions
D. Synthesis of phospholipid fatty-acid tails

45 A fluorescent membrane protein is bleached in a small region. Fluorescence returns only when the protein is experimentally cleaved from its cytoskeletal attachment. What does this result demonstrate?

Organization and Fluid Mosaic Model Hard
A. Phospholipids are covalently attached to the cytoskeleton
B. Protein movement requires ATP-driven transbilayer transport
C. Membrane proteins can move laterally but may be constrained
D. All membrane proteins freely cross between bilayer leaflets

46 A membrane protein is inserted into the endoplasmic reticulum with its large domain facing the ER lumen. After vesicular trafficking to the plasma membrane, where will that domain be located?

Organization and Fluid Mosaic Model Hard
A. Distributed randomly between both surfaces
B. Facing the cytosol
C. Facing the extracellular space
D. Embedded between the two leaflets

47 A membrane protein contains several hydrophobic segments, each approximately 20 amino acids long. Which conclusion is most strongly supported?

Organization and Fluid Mosaic Model Hard
A. It is synthesized exclusively inside the nucleus
B. It is necessarily attached only to the outer leaflet
C. It must function as a peripheral signaling protein
D. It likely spans the bilayer multiple times

48 A lipid-bound fluorescent marker remains confined to one leaflet after extensive lateral diffusion but does not appear in the opposite leaflet. Which process is most limited under these conditions?

Organization and Fluid Mosaic Model Hard
A. Rotation around the lipid's long axis
B. Local association with neighboring lipids
C. Lateral diffusion within the leaflet
D. Transverse diffusion, or flip-flop

49 A microorganism increases the proportion of short, cis-unsaturated fatty acids after a sudden temperature decrease. What is the primary adaptive benefit?

Fluidity of membranes and Factors that affect membrane Fluidity Hard
A. Preventing all diffusion of hydrophobic molecules
B. Increasing membrane crystallization during cooling
C. Eliminating the need for membrane transport proteins
D. Preserving membrane fluidity during cooling

50 Two liposomes have identical lipid compositions, but one contains phospholipids with 16-carbon tails and the other with 20-carbon tails. At a temperature just above both transition temperatures, which liposome generally has greater fluidity?

Fluidity of membranes and Factors that affect membrane Fluidity Hard
A. Both have identical fluidity by definition
B. Fluidity depends only on cholesterol concentration
C. The liposome with 16-carbon tails
D. The liposome with 20-carbon tails

51 A membrane's temperature rises substantially, but its fluidity changes very little. Which compositional response would best explain this observation?

Fluidity of membranes and Factors that affect membrane Fluidity Hard
A. Decreased cholesterol and increased membrane pores
B. Decreased phospholipid content and increased glycocalyx
C. Increased saturated and longer fatty-acid tails
D. Increased cis-unsaturated and shorter fatty-acid tails

52 A membrane receptor binds an extracellular ligand but has no cytosolic catalytic domain. Its cytosolic tail associates with a protein kinase. Which function does this arrangement most directly support?

Membrane proteins and their functions Hard
A. Signal transduction across the membrane
B. Direct passage of ions through the bilayer
C. Covalent synthesis of extracellular phospholipids
D. Nonspecific digestion of membrane proteins

53 A cell loses a membrane protein that binds extracellular matrix fibers and also connects internally to actin. Which cellular property is most directly affected?

Membrane proteins and their functions Hard
A. Replication of nuclear DNA during S phase
B. Conversion of glucose into extracellular glycogen
C. Mechanical linkage between the cytoskeleton and extracellular matrix
D. Direct production of ATP in the mitochondrial matrix

54 A mutation changes a channel protein's selectivity filter but leaves its gating mechanism intact. Which outcome is most likely?

Membrane proteins and their functions Hard
A. The channel loses all dependence on electrochemical gradients
B. The channel becomes a pump that hydrolyzes ATP
C. The channel opens normally but conducts an altered set of ions
D. The channel transfers phospholipids between membrane leaflets

55 An ion has a concentration gradient favoring movement into a cell but an electrical gradient opposing entry. Under what condition will the ion still enter spontaneously?

Active transport and passive transport Hard
A. The inward chemical driving force exceeds the outward electrical force
B. The ion is transported through any integral membrane protein
C. The concentration gradient and electrical gradient must point identically
D. ATP is present, regardless of the transport protein

56 A drug blocks the sodium-potassium pump in an animal cell. Initially, which transport process is most directly impaired before secondary effects become prominent?

Active transport and passive transport Hard
A. Osmotic movement of water through the lipid core
B. Primary active transport of sodium and potassium
C. Simple diffusion of oxygen across the membrane
D. Exocytosis of proteins from the Golgi apparatus

57 A symporter moves glucose into an epithelial cell using the inward sodium gradient, even though glucose concentration is already higher inside. Which statement is correct?

Active transport and passive transport Hard
A. Glucose is transported downhill by simple diffusion
B. Sodium is transported uphill by facilitated diffusion
C. Both solutes move downhill through an ungated lipid pore
D. Glucose is transported uphill by secondary active transport

58 A membrane is permeable to water but not to a large intracellular solute. The intracellular solute concentration increases while extracellular solute concentration remains constant. What is the immediate tendency?

Active transport and passive transport Hard
A. Water leaves the cell, decreasing its osmotic pressure
B. The solute rapidly diffuses out through the lipid bilayer
C. No water movement occurs because water is electrically neutral
D. Water enters the cell, increasing its osmotic pressure

59 A neuron releases neurotransmitter when calcium enters its presynaptic terminal. Which event most directly follows the calcium signal?

Exocytosis and Endocytosis Hard
A. Calcium-triggered fusion of secretory vesicles with the plasma membrane
B. Inversion of the plasma membrane's phospholipid asymmetry
C. ATP-driven transport of neurotransmitter through the lipid bilayer
D. Direct diffusion of vesicles through the extracellular matrix

60 A cell internalizes a receptor-ligand complex in clathrin-coated vesicles. The ligand is later degraded, while the receptor returns to the plasma membrane. Which process explains receptor recovery?

Exocytosis and Endocytosis Hard
A. Diffusion of the receptor through the cytosol
B. Sorting through endosomes followed by recycling exocytosis
C. Replication of the receptor inside the lysosome
D. Passive transport of the receptor across the bilayer