Unit 2: Cell Membrane and Permeability - Practice Quiz

BTS118 — Cell Biology 60 Questions
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1 Which type of molecule forms the main structural layer of most cell membranes?

Chemical components of biological membranes Easy
A. Phospholipids
B. Starch
C. Nucleic acids
D. Glycogen

2 Which part of a phospholipid is attracted to water?

Chemical components of biological membranes Easy
A. The amino acid chain
B. The steroid ring
C. The phosphate head
D. The fatty acid tail

3 Which part of a phospholipid avoids water?

Chemical components of biological membranes Easy
A. The phosphate head
B. The sugar group
C. The glycerol head
D. The fatty acid tails

4 Which molecule helps regulate the fluidity of animal cell membranes?

Chemical components of biological membranes Easy
A. Cellulose
B. DNA
C. Glycogen
D. Cholesterol

5 What is the basic arrangement of phospholipids in a cell membrane?

Organization and Fluid Mosaic Model Easy
A. A protein monolayer
B. A phospholipid bilayer
C. A nucleic acid layer
D. A carbohydrate bilayer

6 Why is the cell membrane described as fluid?

Organization and Fluid Mosaic Model Easy
A. It changes into a solid layer
B. Its molecules can move sideways
C. Its molecules are permanently fixed
D. It contains large water channels

7 What does the term "mosaic" refer to in the fluid mosaic model?

Organization and Fluid Mosaic Model Easy
A. The presence of only one protein type
B. The shape of the nucleus
C. The mix of different membrane molecules
D. The arrangement of cell walls

8 Which membrane component is often found attached to the outside surface of proteins or lipids?

Organization and Fluid Mosaic Model Easy
A. RNA molecules
B. Cellulose fibers
C. DNA strands
D. Carbohydrate chains

9 What generally happens to membrane fluidity when temperature increases?

Fluidity of membranes and Factors that affect membrane Fluidity Easy
A. Fluidity increases
B. Fluidity disappears
C. Fluidity changes into rigidity
D. Fluidity becomes constant

10 Which type of fatty acid usually increases membrane fluidity?

Fluidity of membranes and Factors that affect membrane Fluidity Easy
A. Unsaturated fatty acid
B. Very long sugar chain
C. Phosphate-free fatty acid
D. Saturated fatty acid

11 What effect do saturated fatty acid tails usually have on membrane fluidity?

Fluidity of membranes and Factors that affect membrane Fluidity Easy
A. They dissolve the bilayer
B. They increase fluidity
C. They remove proteins
D. They decrease fluidity

12 What is the main effect of cold temperatures on a membrane?

Fluidity of membranes and Factors that affect membrane Fluidity Easy
A. The membrane becomes more fluid
B. The membrane loses all lipids
C. The membrane becomes less fluid
D. The membrane becomes a carbohydrate layer

13 Which membrane protein helps substances cross the membrane?

Membrane proteins and their functions Easy
A. Digestive protein
B. Contractile protein
C. Storage protein
D. Transport protein

14 What is one function of receptor proteins in a cell membrane?

Membrane proteins and their functions Easy
A. Making DNA copies
B. Receiving chemical signals
C. Digesting food particles
D. Storing genetic information

15 Which membrane protein can act as an enzyme?

Membrane proteins and their functions Easy
A. A phospholipid tail
B. A cholesterol molecule
C. A carbohydrate chain
D. An enzymatic protein

16 What is passive transport?

Active transport and passive transport Easy
A. Movement without cellular energy
B. Movement only through vesicles
C. Movement against all gradients
D. Movement using ATP energy

17 In which direction do substances usually move during diffusion?

Active transport and passive transport Easy
A. From the nucleus outward
B. From water to protein
C. From low to high concentration
D. From high to low concentration

18 What is required for active transport?

Active transport and passive transport Easy
A. Cellular energy
B. Only oxygen gas
C. A concentration balance
D. A cell wall

19 What is endocytosis?

Exocytosis and Endocytosis Easy
A. Breaking down membrane lipids
B. Releasing materials from the cell
C. Taking materials into the cell
D. Moving water through a wall

20 What is exocytosis?

Exocytosis and Endocytosis Easy
A. Releasing materials from the cell
B. Taking materials into the cell
C. Making phospholipids in the bilayer
D. Moving particles through channels

21 A membrane is exposed to a chemical that removes cholesterol while leaving phospholipids intact. Which change is most likely at moderate temperatures?

Chemical components of biological membranes Medium
A. The membrane becomes unable to form a bilayer
B. The membrane becomes less permeable to ions
C. The membrane gains more carbohydrate chains
D. The membrane loses some control of fluidity

22 Why do phospholipids spontaneously form bilayers in an aqueous environment?

Chemical components of biological membranes Medium
A. Their proteins force the lipids into two layers
B. Their hydrocarbon tails attract surrounding water
C. Their phosphate groups avoid contact with water
D. Their hydrophilic heads face water and hydrophobic tails avoid it

23 A membrane carbohydrate is attached directly to a lipid rather than to a protein. What structure has been formed?

Chemical components of biological membranes Medium
A. A glycolipid
B. A glycoprotein
C. A phospholipid
D. A lipoprotein channel

24 A researcher labels proteins on the outer surface of a cell and observes that many labels move laterally after several minutes. Which model best explains this observation?

Organization and Fluid Mosaic Model Medium
A. The fluid mosaic model
B. The rigid wall model
C. The fixed-layer model
D. The protein crystal model

25 A membrane protein is exposed to the cytoplasm on one side and the extracellular fluid on the other. Which property of the membrane does this demonstrate?

Organization and Fluid Mosaic Model Medium
A. Permanent protein immobility
B. Membrane asymmetry
C. Uniform lipid distribution
D. Membrane crystallization

26 A drug binds to membrane proteins but does not dissolve the phospholipid bilayer. Which membrane feature allows the drug to affect selected cell functions?

Organization and Fluid Mosaic Model Medium
A. The membrane prevents all molecular movement
B. The membrane has specialized proteins
C. The membrane contains identical proteins
D. The membrane is made only of carbohydrates

27 Two membranes contain the same number of phospholipids. Membrane X has more unsaturated fatty acid tails than membrane Y. At low temperature, which membrane should remain more fluid?

Fluidity of membranes and Factors that affect membrane Fluidity Medium
A. Membrane Y, because its tails contain fewer bonds
B. Membrane Y, because its tails pack tightly
C. Membrane X, because its heads contain more phosphate
D. Membrane X, because its tails contain bends

28 A cell adapted to a colder environment increases the proportion of unsaturated phospholipids in its membrane. What is the main benefit?

Fluidity of membranes and Factors that affect membrane Fluidity Medium
A. It increases the membrane's carbohydrate content
B. It reduces lateral lipid movement
C. It blocks all small polar molecules
D. It maintains membrane flexibility

29 If membrane temperature rises substantially, which change is most likely to occur without another stabilizing factor?

Fluidity of membranes and Factors that affect membrane Fluidity Medium
A. The hydrophobic tails become charged
B. The bilayer becomes more fluid
C. The bilayer becomes completely solid
D. The phospholipids become proteins

30 A cell accumulates a molecule inside using a membrane protein that changes shape after binding the molecule. Which function is being performed?

Membrane proteins and their functions Medium
A. Transport
B. Cell recognition
C. Membrane digestion
D. DNA replication

31 A membrane protein binds a signaling molecule outside the cell and triggers a response inside the cell without transporting the molecule across. What is its primary function?

Membrane proteins and their functions Medium
A. Phospholipid synthesis
B. Waste digestion
C. Receptor activity
D. Structural storage

32 A protein is attached to the inner surface of the plasma membrane but does not extend through the lipid bilayer. Which type of membrane protein is it?

Membrane proteins and their functions Medium
A. Integral protein
B. Transmembrane channel
C. Lipid bilayer protein
D. Peripheral protein

33 A molecule moves from an area of lower concentration to an area of higher concentration through a membrane protein. Which process is most likely involved?

Active transport and passive transport Medium
A. Facilitated diffusion
B. Active transport
C. Simple diffusion
D. Osmosis

34 A molecule crosses a membrane through a channel protein from high concentration to low concentration without ATP use. Which process describes this movement?

Active transport and passive transport Medium
A. Exocytosis
B. Facilitated diffusion
C. Phagocytosis
D. Primary active transport

35 A cell uses ATP to move sodium ions out of the cytoplasm even though sodium concentration is already higher outside. What does this process illustrate?

Active transport and passive transport Medium
A. Movement through the lipid core
B. Movement down a gradient
C. Solvent movement by osmosis
D. Primary active transport

36 A red blood cell is placed in a solution with a lower solute concentration than its cytoplasm. What is the most likely result?

Active transport and passive transport Medium
A. Water enters and the cell swells
B. Solutes leave and the cell becomes rigid
C. Water leaves and the cell shrinks
D. No water movement occurs

37 A membrane is permeable to water but not to a dissolved solute. Which condition would cause water to move into a cell?

Active transport and passive transport Medium
A. The cell has a lower solute concentration
B. The surrounding solution has no water
C. The solute can freely cross the membrane
D. The cell has a higher solute concentration

38 A secretory cell releases a protein outside the cell when a vesicle fuses with the plasma membrane. Which process is occurring?

Exocytosis and Endocytosis Medium
A. Simple diffusion
B. Osmosis
C. Endocytosis
D. Exocytosis

39 A cell surrounds and internalizes a large bacterium using extensions of its plasma membrane. Which type of endocytosis is this?

Exocytosis and Endocytosis Medium
A. Facilitated diffusion
B. Pinocytosis
C. Receptor-mediated exocytosis
D. Phagocytosis

40 A cell selectively takes in a hormone after it binds to a specific receptor concentrated in a coated membrane region. Which process is most likely involved?

Exocytosis and Endocytosis Medium
A. Primary active transport
B. Simple diffusion
C. Receptor-mediated endocytosis
D. Bulk-phase exocytosis

41 A membrane lipid has two fatty-acid tails: one saturated 18-carbon tail and one cis-unsaturated 18-carbon tail. Compared with a lipid containing two saturated 18-carbon tails, what is the most likely consequence at the same temperature?

Chemical components of biological membranes Hard
A. Lower transition temperature and greater fluidity
B. Lower transition temperature and reduced fluidity
C. No change because both lipids contain 18 carbons
D. Higher transition temperature and greater fluidity

42 A membrane is experimentally made more permeable to small nonpolar molecules without changing its protein content. Which alteration most directly explains this result?

Chemical components of biological membranes Hard
A. Increasing the fraction of membrane carbohydrates
B. Increasing the fraction of peripheral proteins
C. Increasing the fraction of phospholipids
D. Increasing the fraction of unsaturated phospholipids

43 Why does cholesterol reduce membrane permeability to small polar molecules while helping prevent phospholipid packing at low temperatures?

Chemical components of biological membranes Hard
A. Its fatty-acid tails create permanent pores through the bilayer
B. Its steroid rings fill gaps while its hydroxyl group remains near the surface
C. Its phosphate group forms covalent bonds with neighboring phospholipids
D. Its carbohydrate chains bind water and form an external diffusion barrier

44 A researcher treats intact red blood cells with a reagent that removes exposed carbohydrate groups but leaves proteins and lipids intact. Which function is most directly impaired?

Chemical components of biological membranes Hard
A. Recognition during cell-cell interactions
B. Hydrolysis of ATP by cytosolic enzymes
C. Synthesis of phospholipid fatty-acid tails
D. Movement of cholesterol between leaflets

45 A fluorescent membrane protein is bleached in a small region. Fluorescence returns only when the protein is experimentally cleaved from its cytoskeletal attachment. What does this result demonstrate?

Organization and Fluid Mosaic Model Hard
A. All membrane proteins freely cross between bilayer leaflets
B. Protein movement requires ATP-driven transbilayer transport
C. Membrane proteins can move laterally but may be constrained
D. Phospholipids are covalently attached to the cytoskeleton

46 A membrane protein is inserted into the endoplasmic reticulum with its large domain facing the ER lumen. After vesicular trafficking to the plasma membrane, where will that domain be located?

Organization and Fluid Mosaic Model Hard
A. Embedded between the two leaflets
B. Facing the extracellular space
C. Distributed randomly between both surfaces
D. Facing the cytosol

47 A membrane protein contains several hydrophobic segments, each approximately 20 amino acids long. Which conclusion is most strongly supported?

Organization and Fluid Mosaic Model Hard
A. It likely spans the bilayer multiple times
B. It is synthesized exclusively inside the nucleus
C. It is necessarily attached only to the outer leaflet
D. It must function as a peripheral signaling protein

48 A lipid-bound fluorescent marker remains confined to one leaflet after extensive lateral diffusion but does not appear in the opposite leaflet. Which process is most limited under these conditions?

Organization and Fluid Mosaic Model Hard
A. Lateral diffusion within the leaflet
B. Local association with neighboring lipids
C. Rotation around the lipid's long axis
D. Transverse diffusion, or flip-flop

49 A microorganism increases the proportion of short, cis-unsaturated fatty acids after a sudden temperature decrease. What is the primary adaptive benefit?

Fluidity of membranes and Factors that affect membrane Fluidity Hard
A. Preventing all diffusion of hydrophobic molecules
B. Eliminating the need for membrane transport proteins
C. Preserving membrane fluidity during cooling
D. Increasing membrane crystallization during cooling

50 Two liposomes have identical lipid compositions, but one contains phospholipids with 16-carbon tails and the other with 20-carbon tails. At a temperature just above both transition temperatures, which liposome generally has greater fluidity?

Fluidity of membranes and Factors that affect membrane Fluidity Hard
A. The liposome with 20-carbon tails
B. Fluidity depends only on cholesterol concentration
C. The liposome with 16-carbon tails
D. Both have identical fluidity by definition

51 A membrane's temperature rises substantially, but its fluidity changes very little. Which compositional response would best explain this observation?

Fluidity of membranes and Factors that affect membrane Fluidity Hard
A. Decreased phospholipid content and increased glycocalyx
B. Increased cis-unsaturated and shorter fatty-acid tails
C. Increased saturated and longer fatty-acid tails
D. Decreased cholesterol and increased membrane pores

52 A membrane receptor binds an extracellular ligand but has no cytosolic catalytic domain. Its cytosolic tail associates with a protein kinase. Which function does this arrangement most directly support?

Membrane proteins and their functions Hard
A. Signal transduction across the membrane
B. Nonspecific digestion of membrane proteins
C. Direct passage of ions through the bilayer
D. Covalent synthesis of extracellular phospholipids

53 A cell loses a membrane protein that binds extracellular matrix fibers and also connects internally to actin. Which cellular property is most directly affected?

Membrane proteins and their functions Hard
A. Replication of nuclear DNA during S phase
B. Conversion of glucose into extracellular glycogen
C. Direct production of ATP in the mitochondrial matrix
D. Mechanical linkage between the cytoskeleton and extracellular matrix

54 A mutation changes a channel protein's selectivity filter but leaves its gating mechanism intact. Which outcome is most likely?

Membrane proteins and their functions Hard
A. The channel transfers phospholipids between membrane leaflets
B. The channel loses all dependence on electrochemical gradients
C. The channel opens normally but conducts an altered set of ions
D. The channel becomes a pump that hydrolyzes ATP

55 An ion has a concentration gradient favoring movement into a cell but an electrical gradient opposing entry. Under what condition will the ion still enter spontaneously?

Active transport and passive transport Hard
A. The concentration gradient and electrical gradient must point identically
B. The inward chemical driving force exceeds the outward electrical force
C. The ion is transported through any integral membrane protein
D. ATP is present, regardless of the transport protein

56 A drug blocks the sodium-potassium pump in an animal cell. Initially, which transport process is most directly impaired before secondary effects become prominent?

Active transport and passive transport Hard
A. Simple diffusion of oxygen across the membrane
B. Exocytosis of proteins from the Golgi apparatus
C. Primary active transport of sodium and potassium
D. Osmotic movement of water through the lipid core

57 A symporter moves glucose into an epithelial cell using the inward sodium gradient, even though glucose concentration is already higher inside. Which statement is correct?

Active transport and passive transport Hard
A. Glucose is transported downhill by simple diffusion
B. Glucose is transported uphill by secondary active transport
C. Sodium is transported uphill by facilitated diffusion
D. Both solutes move downhill through an ungated lipid pore

58 A membrane is permeable to water but not to a large intracellular solute. The intracellular solute concentration increases while extracellular solute concentration remains constant. What is the immediate tendency?

Active transport and passive transport Hard
A. The solute rapidly diffuses out through the lipid bilayer
B. Water leaves the cell, decreasing its osmotic pressure
C. No water movement occurs because water is electrically neutral
D. Water enters the cell, increasing its osmotic pressure

59 A neuron releases neurotransmitter when calcium enters its presynaptic terminal. Which event most directly follows the calcium signal?

Exocytosis and Endocytosis Hard
A. Direct diffusion of vesicles through the extracellular matrix
B. Calcium-triggered fusion of secretory vesicles with the plasma membrane
C. ATP-driven transport of neurotransmitter through the lipid bilayer
D. Inversion of the plasma membrane's phospholipid asymmetry

60 A cell internalizes a receptor-ligand complex in clathrin-coated vesicles. The ligand is later degraded, while the receptor returns to the plasma membrane. Which process explains receptor recovery?

Exocytosis and Endocytosis Hard
A. Sorting through endosomes followed by recycling exocytosis
B. Passive transport of the receptor across the bilayer
C. Replication of the receptor inside the lysosome
D. Diffusion of the receptor through the cytosol